Artificial Intelligence · 25.08.2026, 04:46 UTC
Dissecting Neuro-Symbolic Quality Assurance for Synthetic Oncology Data Generation
| Schweregrad | info |
|---|---|
| Kategorie | Artificial Intelligence |
| Quelle | arXiv cs.AI ↗ |
| Veröffentlicht | 25.08.2026 UTC |
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arXiv:2608.22085v1 Announce Type: new Abstract: Synthetic clinical data generation with large language models addresses the scarcity that limits cancer staging research, but oncology hallucinations are categorically harmful: one clinically impossible staging assignment contaminates every downstream model trained on it. Neuro-symbolic pipelines validate during generation, yet the contribution of individual quality-assurance components remains unclear. We report three controlled studies isolating gate necessity, constraint attribution, and retrieval conditionality, holding generation protocol, diversity thresholds, and fine-tuning hyperparameters constant across adapter conditions. The symbolic gate enforces schema completeness, ontology coverage against the Systematized Nomenclature of Medicine, and staging-logic consistency under American Joint Committee on Cancer eighth-edition rules. Ungated, 29.9% of records contain schema failures and 20.1% contain clinically invalid staging. Schema validation is the load-bearing filter: within the fully gated corpus it rejects 148 of 512 records, ontology grounding a further 24, and staging-logic validation none---the only generator producing logic violations is already excluded on schema, making clinical-logic validation a generator-conditional safeguard rather than the dominant filter. Retrieval augmentation is strongly model-dependent: it improves gate compliance for one generator by 12.5 percentage points, has no measurable effect for a second, and collapses output in a third. Across gated configurations ontology density is …
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